Preheat your oven to 350°F (175°C). If using a baking sheet, line it with aluminum foil for easy cleanup.
In a large mixing bowl, combine the ground beef, ground pork, cooked bacon, shredded cheddar cheese, breadcrumbs, ketchup, mustard, eggs, chopped onion, minced garlic, salt, pepper, and Worcestershire sauce. Mix until well combined.
Transfer the meat mixture to the prepared loaf pan or shape it into a loaf on the baking sheet.
Bake in the preheated oven for 1 hour, or until the internal temperature reaches 160°F (71°C). If using a meat thermometer, insert it into the center of the meatloaf for an accurate reading.
Once cooked, remove the meatloaf from the oven and let it rest for 10 minutes before slicing.
Serve warm, optionally topped with additional ketchup or cheese.