Preheat the oven to 375°F (190°C).
In a mixing bowl, whisk together the honey, Dijon mustard, olive oil, apple cider vinegar, garlic powder, onion powder, salt, and pepper until well combined.
Place the chicken breasts in a baking dish or oven-safe skillet. Pour the honey mustard mixture over the chicken, making sure each piece is coated.
Bake in the preheated oven for about 25 minutes, or until the chicken is cooked through and reaches an internal temperature of 165°F (75°C). Baste the chicken with the sauce halfway through cooking for extra flavor.
Once cooked, remove the chicken from the oven and let it rest for 5 minutes before slicing. This helps retain juices.
Serve the chicken hot, garnished with fresh parsley if desired, and drizzle with any remaining sauce from the baking dish.